Open Staff Positions
PROGRAM SCIENTIST 1, Biological Engineering – The MIT Center for Gynepathology Research (CGR), under the direction of Drs. Linda Griffith and Michal Tal, in a new program in Engineering Women’s Health involving over a dozen MIT faculty and their collaborators around the world will assist in the development, implementation, and broad dissemination of new immunological assays that capture features of human pathophysiology; and facilitate the day-to-day collaboration of the immunological and computational tool development teams with the engineering and clinical teams to define design criteria for “Novel Alternative Methods (NAMs)” for generating humanized experimental data, and translating extant mouse data to the human condition.
Description, requirements, and details on MIT HR Job Openings.
RESEARCH SPECIALIST, MICROPHYSIOLOGICAL SYSTEMS, Biological Engineering, to join the laboratory of Dr. Linda Griffith, to provide critical support to an ongoing project developing an in vitro tissue-engineered model of innervated endometriotic lesions; develop, record, and execute protocols and experiments for the culture and characterization of iPSC human neurons in a novel microstructured 3D culture platform, then adapt those protocols for co-culture with patient-derived primary endometrial cells including light microscopic, immunofluorescence, and functional characterizations, including signaling (immunofluorescent signal peak analysis, ELISA, Luminex, etc.); contribute to data analysis and writing that will result in publication of the project outcomes; and serve as a liaison between the Griffith lab and other collaborating labs, including the establishment of new collaborations.
Description, requirements, and details on MIT HR Job Openings.
FINANCIAL OFFICER, SPONSORED ACTIVITY, Biological Engineering, to perform complex and comprehensive sponsored research financial management for an assigned portfolio of faculty and serve as the primary informational resource on matters pertaining to sponsored research administration; serve as the primary point-of- contact for assigned faculty; prepare and submit research proposals/contracts, assisting principal investigators with budgets and administrative content; prepare reports, forecast, and disseminate relevant information to faculty and staff; meet with PIs to review budgets and plan financial reports and forecasts; review and approve research proposals; ensure compliance with MIT research administration policies; oversee subawards, cost- sharing, under-recovery, overruns, and other financial issues; coach, mentor, and train staff engaged in sponsored research administration activities; recommend policies and initiatives and develop improvements/innovations to enhance performance; and assist with preparing financial reports as needed.
Description, requirements, and details on MIT HR Job Openings.
POSTDOCTORAL ASSOCIATE, MOLECULAR NEUROSCIENCE, Department of Biological Engineering – Bathe Lab, to help pioneer a new approach in molecular neuroscience based on simultaneous single-synapse multimodal interrogation of the activity and biochemistry of synapse populations. In collaboration with the Stanley Center for Psychiatric Research at the Broad Institute, this individual will work on leveraging technology developed in the Bathe lab to study the molecular etiology of neurodevelopmental and psychiatric disorders and the mechanisms of psychoactive therapeutics and develop tools to extract new information modalities at the single-synapse resolution. The project aims to interrogate cellular models from human patient cell lines to reveal molecular mechanisms of perturbed cognition that will enable psychiatric drug discovery and understanding of cognitive disorders.
Description, requirements, and details on MIT HR Job Openings.
LECTURER, Department of Biological Engineering, to join the department as a Lecturer focused on teaching the computational aspects of biological engineering. Will help develop and deliver courses that integrate computational tools, data analysis, and modeling approaches to address key challenges in biological engineering; and focus on two undergraduate courses that emphasize modern computational approaches to modeling, analysis, genomics, and design: 20.320 Analysis of Biomolecular and Cellular Systems and a new Genomics class being developed.
Description, requirements, and details on MIT HR Job Openings.
PROGRAM SCIENTIST 2, IMMUNOLOGY, Biological Engineering (BE), to help launch and expand a major new program in Engineering Women’s Health; assist in coordinating several interdisciplinary, multi-investigator projects centered on developing, implementing, and broadly disseminating new immunological assays that capture features of human pathophysiology; facilitate the day-to-day collaboration of the immunological and computational tool development teams with the engineering and clinical teams; and assist in strategic planning for creating a core facility, preparing grants and reports, technical content, and organizing contributions from other team members, among other tasks.
Description, requirements, and details on MIT HR Job Openings.
POSTDOCTORAL ASSOCIATE, Biological Engineering (BE), to work on a project that involves studies of interactions among different DNA repair activities and how these interactions shape the biological consequences of exposure to DNA damage. Will perform mouse husbandry for multiple mouse strains; develop methods to visualize clonally expanded cells using 2-photon microscopy in collaboration with TissueVision; handle and treat mice with N-nitrosadimethylamine; perform spatial transcriptomics; study mutagenesis and carcinogenesis; and prepare figures and drafts of manuscripts.
Description, requirements, and details on MIT HR Job Openings.
RESEARCH SCIENTIST 2, Biological Engineering-Synthetic Biology Center-Weiss Lab, to join an interdisciplinary research lab seeking to create integrated biological systems capable of autonomously performing tasks related to the activities of therapeutic agents for a variety of applications, including immunotherapy. Will participate in government- and corporate-sponsored research in mammalian synthetic biology, including genetically encoded therapies that perform cell type classification and conditionally administer appropriate therapeutic molecules. These mammalian genetic circuits will sense cell state, including miRNA levels, and implement multi-input logic regulating the expression of proinflammatory cytokines. Genetic circuits will be encoded on RNA replicons and distinguish between cell types such as lung cancer and T cells. Cell type identification will be based on determining an optimal combination of low and high miRNAs present or absent in the relevant cell types. Another level of control will be based on externally-administered small molecules that modulate the stability of regulatory RNA binding proteins. Will also engineer subgenomic promoters of RNA replicons for optimized tandem expression of constitutive and small molecule-regulated payloads in cancer and immune cells.
Description, requirements, and details on MIT HR Job Openings.
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